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John Hugh MacKerras was born in 1882. He was educated at Queen's University earning a B.A. in 1850 and an M.A. in 1852. In 1864 he was made Professor of Classics at Queen's University. He died in 1880.

William Lyon Mackenzie, journalist and politician, was born in 1795, at Dundee, Scotland. Mackenzie arrived in Upper Canada from Scotland in 1820. He began his newspaper, the Colonial Advocate, in Queenston in 1824. He moved to York in 1824 and was elected to the Assembly in 1828. Mackenzie's harsh criticism of the Family Compact, a small group of men who controlled the colony, gained him a large following among the people. Friends of the Family Compact retaliated with threats and legal action. In 1834 York became the city of Toronto and Mackenzie became its first mayor. By this time Mackenzie's views had become more extreme. In 1837 he led a rag-tag group of rebels down Yonge Street. Only a few shots were fired and the rebels scattered. Mackenzie evaded capture and fled to the United States. He tried unsuccessfully to organize a new scheme from Navy Island on the Niagara River. He was put in prison by the Americans. After his release he worked as a journalist in the United States and wrote several books. Mackenzie was pardoned and he returned to Canada in 1849. He resumed his career as a journalist and was again elected as an MLA. He kept up his fiery criticism until his death in 1861 at Toronto. Mackenzie's grandson, William Lyon Mackenzie King, became prime minister of Canada.

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Norman A.M. MacKenzie, CC CMG MM CD QC FRSC (January 5, 1894 – January 26, 1986) was the President of the University of British Columbia from 1944 to 1962, and a Senator from 1966 to 1969. He was born in Pugwash, Nova Scotia. He fought during World War I. He studied law at Dalhousie, Harvard and Cambridge Universities. In 1927, he went to the University of Toronto, where he taught law for thirteen years. He became president of the University of New Brunswick in 1940. He was president of the University of British Columbia from 1944 to 1962. In 1959 he hosted Queen Elizabeth at the University of British Columbia's Faculty Club. He was a member of the Senate from 1966 to 1969 representing the senatorial division of University-Point Grey, British Columbia. In 1969 he was made a Companion of the Order of Canada. He and his wife, born Margaret Thomas (1903–1987), had three children: Bridget Mackenzie (?-present), Susan Mackenzie (1928–present), and Patrick Thomas Mackenzie (1932-Jan 23 2006).

Frederick Donald MacKenzie was born in 1882 at Presque Ile, Ontario. He attended Queen's University to World War I and joined Queen's University Contingent, C.O.T.C. in 1914. He was posted to the Queen's Medical Unit, Number 5, Stationary Hospital and sent to Cairo, Egypt. After taking officer training he ended up an officer in the Canadian artillery. On demobilization he took up residence in Manitoba where he taught school and was a school principal for a short time. In 1935 he was elected Member of Parliament for Neepawa, Manitoba as a Liberal and he served in the House of Commons until 1945.

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Frederick Donald (Don) (B.A. '15) MacKenzie was born in Presqu'Isle, Ontario. He attended Queen's University at Kingston, and volunteered for duty overseas with No.5 Stationary Hospital when the unit was raised by the University during World War One.

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